Bupropion is a medication most often prescribed to treat depression or to help quit smoking. It can also be used to treat ADHD, bipolar depression, and seasonal affective https://rehabliving.net/alcohol-use-disorder-and-ptsd-an-introduction-pmc/ disorder. Common brand names of bupropion products include Wellbutrin®, Zyban®, and Contrave®. A bupropion/naltrexone combination (Contrave®) might help with weight loss.
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Advise families and caregivers of the need for close observation and communication with the prescriber BuPROPion hydrochloride extended-release tablet is not approved for use in pediatric patients. Although WELLBUTRIN is not indicated for smoking cessation treatment, it contains the same active ingredient as ZYBAN® which is approved for this use. Advise patients, families and caregivers that quitting smoking, with or without ZYBAN, may trigger nicotine withdrawal symptoms (e.g., including depression or agitation), or worsen pre-existing psychiatric illness.
- Also tell your doctor if you have sudden or strong feelings, such as feeling nervous, angry, restless, violent, or scared.
- Wait for 2 weeks after stopping bupropion before you start taking a MAO inhibitor.
- One of the components of Contrave blocks the action of opioid pain medication such as morphine or oxycodone, meaning you will not have your normal pain relief.
- When used concomitantly with WELLBUTRIN, it may be necessary to decrease the dose of these CYP2D6 substrates, particularly for drugs with a narrow therapeutic index.
- Do not take this medicine to treat more than one condition at a time.
- To help avoid interactions, your doctor should manage all of your medications carefully.
What is Wellbutrin XL?
Your doctor may need to check your weight on a regular basis. Check with your doctor right away if blurred vision, eye pain, or any other change in vision occurs during or after treatment. Your doctor may want your eyes be checked by an ophthalmologist (eye doctor). This medicine may cause some people to have a false sense of wellbeing, or to become drowsy, dizzy, or less alert than they are normally. Make sure you know how you react to this medicine before you drive, use machines, or do anything else that could be dangerous if you are drowsy, dizzy, or less alert. Your blood pressure might get too high while you are using this medicine.
What is bupropion?
Tell them about all prescription, over-the-counter, and other drugs you take. Also, tell them about any vitamins, herbs, and supplements you use. Sharing this information can help you avoid potential interactions. For SAD, you may take Wellbutrin XL for short periods during the year.
Side effects
If you drink alcohol, talk with your doctor about whether this drug is safe for you. Alcohol or marijuana (cannabis) can make you more dizzy or affect your coordination. Before taking bupropion, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies.
The drug comes in sustained-release (SR) and extended-release (XL) tablets for swallowing. Take this medication by mouth with or without food as directed by your doctor, usually three times daily. If stomach upset occurs, you may take this drug with food. It is important to take your doses at least 6 hours apart or as directed by your doctor to decrease your risk of having a seizure. Bupropion is a norepinephrine and dopamine reuptake inhibitor used in the treatment of major depressive disorder (MDD), seasonal affective disorder (SAD), and as an aid to smoking cessation.
Certain antidepressants (MAOIs, SSRIs), antipsychotics (haloperidol, risperidone), and heart medications (beta-blockers, antiarrhythmics) can interact with bupropion. Speak with your pharmacist and doctor to make sure the other medications you take do not interact with bupropion. After your starting dose, your doctor may increase your dose of Wellbutrin SR, which you’ll take twice per day. But certain other antidepressants are approved to treat generalized anxiety disorder. These include escitalopram (Lexapro) and paroxetine (Paxil). Bupropion oral tablet is used for long-term treatment of depression or SAD.
Pre-existing glaucoma is almost always open-angle glaucoma because angle-closure glaucoma, when diagnosed, can be treated definitively with iridectomy. Open-angle glaucoma is not a risk factor for angle-closure glaucoma. Patients may wish to be examined to determine whether they are susceptible to angle closure, and have a prophylactic procedure (e.g., iridectomy), if they are susceptible [see Warnings and Precautions (5.7)]. The exact mechanism of the antidepressant action of bupropion is not known, but is presumed to be related to noradrenergic and/or dopaminergic mechanisms. Bupropion is a relatively weak inhibitor of the neuronal reuptake of norepinephrine and dopamine, and does not inhibit the reuptake of serotonin.
The estimated background risk for major birth defects and miscarriage is unknown for the indicated population. All pregnancies have a background risk of birth defect, loss, or other adverse outcomes. In the U.S. general population, the estimated background risk of major birth defects and of miscarriage in clinically recognized pregnancies is 2% to 4% and 15% to 20%, respectively. The pupillary dilation that occurs following use of many antidepressant drugs crack vs coke including WELLBUTRIN may trigger an angle-closure attack in a patient with anatomically narrow angles who does not have a patent iridectomy. Conversely, at least 14 days should be allowed after stopping WELLBUTRIN before starting an MAOI antidepressant [see CONTRAINDICATIONS, DRUG INTERACTIONS]. It is generally agreed that acute episodes of depression require several months or longer of antidepressant drug treatment beyond the response in the acute episode.
Signs of an overdose include losing consciousness, fever, hallucinations, and muscle pain. One of the biggest concerns is seizures, which happen in 1/3 of bupropion overdoses. If someone might have overdosed on bupropion, take them to a hospital immediately. People who overdose https://sober-home.org/crack-cocaine-withdrawal-symptoms-timeline-detox/ on bupropion are also at risk for heart problems and the loss of their ability to breathe on their own. If you’re not certain whether to skip or take a missed dose, ask your pharmacist. A double dose can increase your risk of serious side effects such as seizures.
